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    Roche May Be First to Dry-AMD Market With Biomarker Focus

    by Elizabeth Krutoholow   Roche may be able to overtake Otsuka in the race to market in geographic atrophy (GA), by leveraging a biomarker test for lampalizumab to structure a smaller pivotal trial, or to garner a breakthrough designation with the FDA, according to Bloomberg Industries. The company will update investors on plans later this [...]

    Buyers Renew Gold Bets as New Fed Chair Looms

    Investors are increasing bets on structured notes that profit on gains in gold, as its price rebounds on the prospect of the Federal Reserve keeping interest rates low and the U.S. taking military action in Syria. Banks in August sold $107.4 million of U.S. notes tied to gold or companies that mine the precious metal, [...]

    Comstock Seeks to Alter Terms of $500 Million Revolver

      Comstock Resources is seeking to lower the interest rate and expand the size of its $500 million revolving line of credit in the fourth quarter. Click Here For More

    Onyx Takeover May Intensify Interest in Oncology Drug Companies

    by Andrew Berens, MD & Thomas Smith, Bloomberg Industries   Amgen’s $10.4 billion purchase of Onyx demonstrates an appetite among biotech and pharma for companies with commercialized products and an oncology pipeline. Other oncology-focused biotechs with at least one commercialized product include Incyte, Seattle Genetics, Medivation and Ariad, each with a market value of $3 [...]

    Fixed-Income Flight Sends Sales to 11-Year Low

    Global sales of structured notes in August are on pace to fall to an 11-year low as investors shun the securities amid concern that fixed-income assets will be hurt by a tapering of the Federal Reserve’s bond purchases. Banks sold $2.18 billion of the securities in Europe and Asia through August 28, down from $6.9 [...]

    Discovery Seeks Emerging Managers

    Discovery Capital Management LLC, the fund of separately managed accounts firm that was last year acquired by Direct Access Group LLC, plans to add as many as five emerging managers for allocations by year end, according to Donald Motschwiller, a partner at the New York-based firm. Click here to continue reading.

    Blocked AMR Deal Costs Bondholders

    Municipal-bond investors are among the biggest losers from the Justice Department’s suit to block a planned $11.5 billion merger between US Airways Group Inc. and AMR Corp., parent of American Airlines. Click here to continue reading.

    U.S. Dollar Being Influenced by Longer-Term Interest Rates

    Currency traders should be paying more attention to the middle and the long end of the U.S. Treasury curve than the short end. To continue reading click here

    Payers Should Not Restrict Total Knee Replacement Surgery, Study Finds Cost Effective

    by Elizabeth Krutoholow Total knee replacement surgery is a cost-effective treatment and should not be restricted for appropriate patients by payers looking to save money as demand for the procedure increases, said Dr. Joshua Jacobs, president of the American Academy of Orthopaedic Surgeons. This rise in demand is driven by the fact that total knee [...]

    Investors Try to Replace Yield as Notes Redeemed

    U.S. investors are increasingly losing attractive terms on structured notes as banks redeem more of the securities this year because of their improving health and soaring stock markets. Issuers have called $5.74 billion of notes in 2013, 42 percent more than the $4.05 billion through the same period last year, according to data compiled by [...]

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